Sugar acids and derivatives
Medchemexpress LLC IFN-beta Rhesus Mac 100ug
IFN-beta Protein is an immunomodulatory cytokine of the type 1 interferon family IFN-beta Protein reduces joint inflammation by inhibiting the RANKL-c-Fos signaling pathway IFN-beta Protein regulates mitochondrial fission through STAT5 PGAM5 and Drp1 to rescue neurodegeneration IFN-beta Protein Rhesus Macaque (HEK293 Fc) is the recombinant Rhesus Macaque-derived IFN-beta protein expressed by HEK293 with C-mFc labeled tag
Medchemexpress LLC D-Glucuronic acid | 6556-12-3 | 1 ML
D-Glucuronic acid is a crucial component of various anti-inflammatory proteoglycans, playing a role in embryonic development and inhibiting cell aggregation. This compound and its derivatives are known for their liver detoxifying properties and have demonstrated anti-tumor activity.
- Promotes early embryonic development
- Inhibits cell aggregation
- Functions as a liver detoxifier
- Derivatives possess anti-tumor activity
- Activates Toll-like receptor 4 (TLR4)
Medchemexpress LLC IL-18RAP Rhesus Mac 10ug | 10ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
Medchemexpress LLC 4-Methylumbelliferyl sulfate potassium | 15220-11-8 | 99.3% | 294.32 | 1 G
4-Methylumbelliferyl sulfate potassium is a fluorescent substrate commonly employed in biochemical and biomedical research to detect sulfatase activity. It comprises a sulfate group linked to a fluorescent molecule, which sulfatase enzymes can cleave. The cleavage of 4-Methylumbelliferyl sulfate releases a highly fluorescent product detectable via fluorescence microscopy or spectroscopy, enabling accurate detection and quantification of these enzymes in various biological samples.
- Fluorescent substrate
- Detects sulfatase activity
- Used in biochemical and biomedical research
- Enables accurate detection and quantification of enzymes
- Detectable via fluorescence microscopy or spectroscopy
Medchemexpress LLC Propionylpromazine-d6 hydrochloride | 1262770-67-1 | 99.8% | 382.98 g/mol | C20H19D6ClN2OS | 10 MG
Propionylpromazine-d6 hydrochloride is the deuterium-labeled (d6) isotopologue of propionylpromazine hydrochloride supplied as the hydrochloride salt. It is intended for use as a tracer or internal standard in quantitative analyses by NMR, GC-MS, or LC-MS, and is suitable for research involving dopamine receptor pharmacology.
- Deuterium-labeled internal standard (d6).
- Hydrochloride salt form for stability and solubility.
- High purity suitable for quantitative analysis (99.8%).
- Useful as tracer for NMR, GC-MS, and LC-MS methods.
- Available in small analytical pack sizes for laboratory use.
![Medchemexpress LLC Sar-[D-Phe8]-des-Arg9-Bradykinin | 126959-88-4 | MFCD05662308 | 100.0% | 975.10 g·mol⁻¹ | C47H66N12O11 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244666.png-250.jpg)
Medchemexpress LLC Sar-[D-Phe8]-des-Arg9-Bradykinin | 126959-88-4 | MFCD05662308 | 100.0% | 975.10 g·mol⁻¹ | C47H66N12O11 | 10 MG
Sar-[D-Phe8]-des-Arg9-Bradykinin is a synthetic peptide agonist of the bradykinin B1 receptor used in pharmacology research to study B1-mediated vascular contractility and inflammatory signaling. It is supplied as a white to off-white solid with defined sequence and characterized physicochemical properties for in vitro applications.
- High purity (99.96%).
- White to off-white solid appearance.
- Molecular weight 975.10 g·mol⁻¹.
- Sequence: {Sar}-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe.
- CAS number 126959-88-4.
- Soluble in DMSO at 100 mg/mL; may require ultrasonic.
- Store sealed at -80°C (up to 2 years) or -20°C (up to 1 year).
- Available in multiple mg sizes (5 mg-100 mg).
Medchemexpress LLC Beta-D-glucopyranosyl nitromethane | 81846-60-8 | MFCD08703736 | 99.5% | C7H13NO7 | 10MG
Beta-D-Glucopyranosyl nitromethane is a glycosyl derivative of nitromethane used in chemical research and synthesis. Supplied as a high-purity solid reagent, it serves as a synthetic intermediate, analytical reference, and building block for studies in carbohydrate chemistry and nitroalkane transformations.
- High reported purity for reliable reactions and analyses.
- Water-soluble solid compatible with aqueous and common organic solvents.
- Available in small laboratory pack sizes for flexibility in experimental scale.
- Well characterized with a defined molecular formula for reference.
- Suitable as a synthetic intermediate and analytical reference standard.
Medchemexpress LLC Integrin alpha V bet 100ug | 100ug
Integrin alpha V beta 6 Protein part of the integrin alpha chain family is featured Integrin alpha V beta 6 Protein Rhesus Macaque (HEK293 His) is a recombinant protein dimer complex containing Rhesus Macaque-derived Integrin alpha V beta 6 protein expressed by HEK293 with C-His labeled tag Integrin alpha V beta 6 Protein Rhesus Macaque (HEK293 His) has molecular weight of 90-140 kDa
Medchemexpress LLC Fenclofenac 25mg | 34645-84-6 | 25 MG
Fenclofenac is a nonsteroidal anti-inflammatory drug (NSAID) supplied as a research-grade analytical standard for inflammation studies. It exhibits antipyretic and analgesic activity and is provided as a white to off-white solid.
- High purity (99.1%).
- Molecular weight 297.13 g/mol.
- Chemical formula C14H10Cl2O3.
- White to off-white solid for analytical use.
- Packaged as 25 MG vials, multiple sizes available.
- Store sealed, away from moisture; follow recommended cold storage for solutions.
Medchemexpress LLC Mosapride citrate dihydrate | 636582-62-2 | 99.6% | 25 MG
Mosapride citrate dihydrate is a gastroprokinetic agent that acts as a 5-hydroxytryptamine4 receptor agonist. It has been extensively used in research related to various gastrointestinal disorders. This compound also potently inhibits Kv4.3 in a concentration-dependent manner, with an IC50 value of 15.2 μM. In vivo, it specifically stimulates upper gastrointestinal motility.
- Acts as a 5-hydroxytryptamine4 receptor agonist
- Used in research for gastrointestinal disorders
- Potently inhibits Kv4.3
- Selectively stimulates upper gastrointestinal motility in vivo
Medchemexpress LLC Diethylstilbestrol-d8 | 91318-10-4 | MFCD01074086 | 99.7% | C18H12D8O2 | 10MG
Diethylstilbestrol-d8 is the deuterium-labeled analogue of diethylstilbestrol supplied as a high-purity powder for research and analytical use. It is intended as a stable isotope internal standard for LC-MS, pharmacokinetic studies, and quantitative assays where mass differentiation from the parent compound is required.
- High isotopic purity suitable for mass spectrometry internal standard.
- Purity 99.7% as supplied.
- Molecular formula C18H12D8O2 and molecular weight 276.40.
- Recommended solvent: DMSO, 50 mg/mL with ultrasonic and warming.
- Storage: powder -20°C (3 years) or 4°C (2 years); in solvent -80°C (6 months) or -20°C (1 month).
- Supplied in small research pack sizes appropriate for analytical workflows.
Medchemexpress LLC Intestinal Alkaline Phosphatase Antibody (YA1559) | 100 UL
Intestinal Alkaline Phosphatase Antibody (YA1559) is a rabbit-derived, non-conjugated IgG monoclonal antibody targeting Intestinal Alkaline Phosphatase. This antibody is designed for research applications, including Western Blot (WB) and Immunohistochemistry-Paraffin (IHC-P).
- Host: Rabbit
- Clonality: Recombinant, monoclonal
- Reactivity: Human
- Isotype: IgG
- Conjugation: Non-conjugated
- Purification: Affinity chromatography
- Form: Liquid
- Storage: Stored at -20°C for 1 year, avoid repeated freeze/thaw cycles
- Application: WB (1:500-1:1000), IHC-P (1:50-1:100)
- Function: Alkaline phosphatase that can hydrolyze various phosphate compounds
- Immunogen: Synthesized peptide derived from human intestinal alkaline phosphatase
Medchemexpress LLC Guanylyl cyclase beta 1 antibody (YA2147) | 100 UL
Guanylyl Cyclase beta 1 Antibody (YA2147) is a Rabbit-derived, non-conjugated IgG monoclonal antibody targeting Guanylyl Cyclase beta 1. This recombinant monoclonal antibody is for research use only and is not intended for sale to patients. It reacts with human, mouse, and rat species.
- Immunogen is a synthesized peptide derived from human guanylyl cyclase beta 1 aa1-64.
- Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide, and 0.05% BSA.
- Related gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP to cGMP.
- Encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs.
- Storage conditions: Store at -20°C for 1 year, avoid repeated freeze/thaw cycles, and is shipped with blue ice.